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If you’re experiencing severe abdominal pain, fever, or heavy bleeding, call 911.

Diseases of the Pancreas

Diseases of the Pancreas Explained

The pancreas plays a critical role in digestion and blood sugar control. Pancreatic diseases include inflammatory conditions (acute and chronic pancreatitis), functional issues like exocrine pancreatic insufficiency, structural problems such as pancreatic cysts or tumors, and genetic disorders like cystic fibrosis that significantly affect the pancreas. This overview page helps patients understand the major categories and points them to more detailed condition pages for specific diagnoses.

Symptoms

Depending on the specific disease, pancreatic problems can cause abdominal pain, difficulties with digestion, changes in stool, weight loss, or blood sugar abnormalities.

Symptoms include:
Upper abdominal pain that may radiate to the back
Nausea and vomiting
Oily or floating stools and bloating
Unintended weight loss
New or difficult-to-control diabetes

When to call

Call the office if you have persistent upper abdominal pain, unexplained weight loss, oily or difficult-to-flush stools, or new blood sugar problems, especially with a personal or family history of pancreatic disease.

Seek emergency care for sudden severe abdominal pain, persistent vomiting, high fever, jaundice, or signs of shock (confusion, fainting, rapid heart rate).

Evaluation & Tests
Management & Treatment

Evaluation is tailored to the suspected condition and may include blood tests, stool tests, CT or MRI scans, endoscopic ultrasound, and other imaging to assess the pancreas and surrounding structures.

Thorough history and exam focused on pain, digestion, and metabolic symptoms
Blood tests (enzymes, blood sugar, nutritional markers)
Cross-sectional imaging (CT/MRI) and/or ultrasound
Endoscopic procedures when needed (ERCP, EUS)
Referral to a gastroenterologist or pancreas specialist for complex or unexplained findings

Treatment depends on the specific diagnosis and may involve lifestyle changes, medications (including enzymes or diabetes medications), endoscopic procedures, surgery, or cancer-directed therapies.

Correct diagnosis to target treatment appropriately
Pain control, nutrition support, and enzyme therapy when digestion is affected
Procedures or surgery for gallstones, cysts, or tumors where appropriate
Close coordination among gastroenterology, surgery, oncology, and nutrition teams
Ongoing monitoring to detect progression or complications
This information is for general educational purposes only and is not a diagnosis or personalized medical advice. It does not replace a visit with your own healthcare provider. Always follow the specific recommendations given by your medical team. If you have urgent or worsening symptoms, contact your provider or seek emergency care right away.

At-a-glance

Abdominal painBloating / gasDiarrheaWeight loss / anemia

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Information on this website is for education only and not a substitute for medical advice.

If you’re experiencing an emergency, call 911.
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