Before starting infusion therapy, you may have blood tests, stool tests, and sometimes imaging or endoscopy to confirm the diagnosis and check for infections. Certain vaccines or screening tests (such as TB or hepatitis) may be needed before the first dose.

For most infusion days, there is no special fasting prep—you can usually eat and drink normally unless told otherwise. Bring an up-to-date medication list, and follow any instructions about holding specific medicines the day of infusion. Dress comfortably and consider bringing a book, headphones, or device to pass the time.

At each visit, you check in, have your vital signs taken, and review any new symptoms or infections with the nurse. An IV line is placed in a vein in your arm or hand. Premedications may be given if ordered. The biologic medicine is then infused slowly through the IV while you sit or recline in a comfortable chair.

Nurses monitor you throughout the infusion for side effects such as itching, flushing, headache, or changes in blood pressure. After the infusion finishes, you may be observed for a short period to ensure you feel well before going home.

Most patients feel well enough to return to normal activities later the same day. Mild fatigue, headache, or temporary aches can occur and usually improve with rest. Serious infusion reactions are uncommon but can include shortness of breath, chest tightness, rash, or severe dizziness—tell staff immediately if you feel unwell during or after an infusion.

Your provider will follow your symptoms, labs, and sometimes imaging or endoscopy to see how well your IBD or autoimmune condition responds over time and will adjust the dose or schedule if needed.